Cancer Treatment: Indole-3-Carbinol (I3C) and Isocyanates


Vitamins and Extracts
Conjugated Linoleic Acid CLA
Ellagic Acid
Intravenous C
Vitamin B17
Vitamin V
Chrysin (Aromatase Inhibitor)

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Indole-3-Carbinol (I3C) and Isocyanates

Cell culture studies have shown I3C and DIM to induce apoptosis (cell death) in prostate, breast and cervical cancer cells. There is also some cell culture evidence that they can inhibit the spread of cancer cells into normal tissue, as well as the angiogenesis (growth of new blood vessels) required by tumors for rapid growth.

It is also possible that I3C is effective against other forms of cancer. One cell culture study has shown that I3C inhibits the proliferation of human colon cancer cells. In animal studies, I3C has been shown to inhibit the development of cancer when given before or simultaneously with a carcinogen. However, in some instances, I3C promotes the development of cancer when given after a carcinogen. These paradoxical results have led some experts to advise against the use of I3C and DIM supplements as cancer preventative supplements until they are better understood.

DIM is a major active acid-catalyzed derivative of one of the phytochemicals in cruciferous vegetables, indole-3-carbinol (I3C). Cruciferous vegetables include broccoli, cauliflower, Brussels sprouts, turnips, kale, green cabbage and mustard seed.

Ellagic Acid Cancer Treatment

Isocyanates are formed from the breakdown of various sulphur-containing compounds known as glucosinolates, found in cruciferous vegetables. Different crucifers contain different glucosinolates, resulting in different isocyanates. Crucifers include brassicas such as broccoli, cauliflower, cabbage, Brussels sprouts, collard greens, mustard, kale, kohlrabi, rutabaga, turnips, bok choy and Chinese cabbage. Other cruciferous vegetables are radish, horse radish, garden cress, watercress, wasabi, and arugula.

Epidemiological studies have shown that diets high in cruciferous vegetables are associated with a reduced risk of several forms of cancer. However, crucifers are high in other anti-cancer compounds, such as vitamin C, carotenoids, selenium, folate, and fibre. I3C is an isocyanate derived from the breakdown of glucobrassicin, a glucosinolate found in a number of common brassicas, the highest concentrations being present in Brussels sprouts, garden cress, mustard greens, and turnip. I3C can combine in the acidic environment of the stomach to form other compounds, such as 3,3''di-indolylmethane (DIM).

Preliminary human trials show that I3C supplementation is helpful in treating conditions related to human papilloma virus (HPV) infection, such as the pre-cancerous cervical intra-epithelial neoplasia (CIN, also called cervical dysplasia) and recurrent respiratory papillomatosis (RRP). In one trial, 30 women with pre-cancerous CIN were given 12 weeks of I3C supplementation or a placebo. Complete regression of CIN was found in 50% of the women taking 200 mg per day and 44% of the women taking 400 mg per day. None of the women who took a placebo experienced a complete regression.

Both I3C and DIM are known to affect oestrogen metabolism, helping its elimination from the body. I3C has also been shown in cell culture studies to boost the production of certain proteins that inhibit the formation of breast and prostate cancer by repairing damaged DNA. Two forms of breast cancer are commonly described – those that depend on oestrogen for their growth, and those that do not. I3C inhibits the proliferation of both kinds of breast cancer cells, while the commonly used breast cancer drug, Tamoxifen, only inhibits proliferation of the oestrogen-dependent form.

In cell culture studies, a combination of Tamoxifen with I3C functions better against breast cancer cells than either of the two alone. Broadly speaking, the effect of I3C and DIM supplements on the risk of other cancers is unknown. Moreover, since little I3C and DIM reaches internal bodily tissues after oral intake, it is uncertain whether I3C and DIM supplementation has any effect on cancer risk. High doses (800 mg/day) of I3C and DIM supplements have been associated with disequilibrium and tremor, which disappears on reduction of the dose. Other minor side effects, such as skin rash, have also been reported. There is also the possibility that I3C and DIM supplements may indirectly help in the metabolism and elimination of many drugs, perhaps decreasing their efficacy.

The breakdown of glucobrassin to I3C is mediated by an enzyme also found in brassicas, but which is deactivated by boiling. Being water soluble, glucosinolates are also leached into cooking water by boiling. The means of brassica consumption therefore has an effect on their efficacy in an anti-cancer role.

DIM is generally much more effective than I3C -- and less expensive. In the mid-1990s it was determined that IC3 was biologically inactive until converted to DIM, which in humans occurs in the digestive tract. I3C is converted into DIM through a process involving gastric hydrochloric acid (HCL). If a person is deficient in HCL, as commonly occurs in the elderly, I3C will not effectively convert into DIM. In contrast to I3C, DIM is highly stable, does not need any conversion in stomach acid, and is by far the most active phytochemical in promoting the synthesis of protective 2OHE. However, DIM is poorly absorbed unless "absorption enhanced" in some way. Please look for such wording on any DIM product you consider purchasing.

It is generally agreed that 300mg of IC3 converts to 30-40mg of DIM. As little as 0.5-2mg per kg of body weight per day of DIM has been demonstrated to be an effective dose. A typical dose is 40-60mg once or twice a day.

Complement a Indole-3-Carbinol (I3C) / DIM treatment with a Royal Rife Digital Machine.

Dr. Royal Raymond Rife Created the Original ''Royal Rife Machine'', A frequency generating device which was used to cure terminally ill cancer patients through selective electronic frequency treatment programs... See below:

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The Rife Professional Series use specific frequencies from the 3500 frequency list book to stimulate a altering of bioresonance in the cells, reversing the change caused by the disease. Transmitting these frequencies over the same electrodes (straps) over a period of time generates healing signals that have the curative effect. With this method of treatment, practitioners claim to be able to detect and cure a variety of diseases and addictions without drugs.

Used successfully in Germany for more than 16 months, and with over 20000 users, The Rife Digital Professional V2 series is a German model which is now available to USA. The Rife Digital Professional V2 specializes in running all of the Bioresonance frequencies pertaining to Dr Rife's original machine. It is a higher powered device using 19v DC, 4500ma, averaging an output of about 17.5 volts and 1 million Hertz frequencies to the body. This model comes into alignment with the standard industry Rife Machines now available for many thousands of dollars more, Rife Digital Professional now incorporates Carrier Wave, and Radio Frequency Switchable options to name a few new features.

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The Rife Machine Series

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Purchase Rife Digital Ultimate Trio model if .....

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Dr Rife Professional Machine V2
Professional Rife Machine Harmonics Professional Rife Machine Crystal

- Larger 30MHZ Quartz Crystal Core

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- Power Rating: 19v-DC, (Ultimate model has 35% x more Power than Rife Digital Bioresonanz)
- Power Adapter Rating: 4500ma, (Professional model has 125% x more Amp Capacity)
- Voltage Variable
- Rife Measured Voltage Output ~12.5, 14.5 and 17.5v  (Use only Oscilloscope to measure voltage output)
- 50% Duty Cycle (Standard)
- 100% Positive Offset
- DAC: Digital Accuracy
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- Frequency Range: 0000.01Khz - 0999.99Khz (≈ 1MHz)
- Lab tested Pure Square Waveform on all Rife frequencies
- Harmonics: Harmonic Waveform periodic on 100% of Frequencies
- Square Wave Output
- 2 Strap Connectors for the hands and feet.
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- USA manufactured chipsets, by Microchip Devices USA
- All Countries DC Switching mode Power Supply Adapter (US110v - 230/240/250v)
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Purchase Rife Digital Professional V2 model if .....

(1) You wish to use the Higher Power output of the new PULSE feature
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"Rife Digital Professional V2 Machine was born from Dr Royal Rife's discoveries: A machine that provided the exact frequencies produced by Dr Rife's original Clinic model"
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. are the only company selling the Professional Series, based on Dr Rife's original Rife Machine

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